«A VERY SUITABLE FIRST-LINE THERAPY FOR MENOPAUSAL COMPLAINTS.»
DOCTORS ABOUT MENAPUL®
Prim Univ.-Prof. Dr. Martin Imhof
(Department for gynecology, General Public Teaching Hospital Korneuburg, Austria)
«The study has confirmed that an early, individualized therapy provides clear benefit. This significant scientific study allows us to show that MF11RCE®-Isoflavone considerably reduces menopausal complaints without side effects. MF11RCE® thus appears to be a very suitable first-line therapy for menopausal complaints and, based on its effectiveness as a “selective estrogen receptor modulator” (SERM), forms the ideal prerequisites to also complement a synthetic estrogen.»
Lipovac M. et al., Gynecol Endocrinol. 2012 Mar 28(3): 203-207.
Univ.-Prof. Dr. Christian Simhandl
(Bipolar center Wiener Neustadt, Austria)
«The study shows that with red clover extract psychological complaints such as anxiety and depression in menopause can be successfully and expediently tackled without hormone replacement therapy or psychotropic treatment. In 109 women, the changes in the parameters related to depression and anxiety collected in the self-assessment were clearly and clinically relevant compared to the placebo. We should thus be encouraged to successfully treat psychological complaints like anxiety and depression with red clover extract in the early stages of menopause.»
Lipovac M. et al. Maturitas 2010 Mar 65(3): 258-261.
Dr. Peter Chedraui
(Medical University de Santiago de Guayaquil, Ecuador)
«After three months of MF11RCE® supplements, the women reported a subjective improvement to their scalp and the condition of their skin. In addition to this, their libido, mood, sleep and levels of tiredness improved. It is interesting to note that this is just the first study which demonstrates the effectiveness of MF11RCE® on post-menopausal women. It shows MF11RCE® to be an attractive therapeutic option, in particular for women for whom a conventional estrogen therapy is contraindicated, or for those for whom it is not suitable.»
Chedraui P. et al. Int J Gynaecol Obstet. 2006 Dec 95(3): 296-7.
Univ.-Prof. Dr. Dr. h.c. Heinz Kölbl
(Department for general gynecology and gynecological oncology, Medical University of Vienna, Austria)
«The present results emphasize the significance of the urogenital atrophy and its treatment. The data relating to treatment with red clover extract (MF11RCE®) is compelling. The key symptoms of vaginal dryness and increase in libido go hand in hand with the evidence of cytological changes as hard parameters of effectiveness. These studies should provide motivation to study the favorable effects of the substance also with regard to functionality of the pelvic organs (bladder, bowels).»
Chedraui P. et al. Int J Gynaecol Obstet. 2006 Dec 95(3): 296-7.
Univ.-Prof. DDr. Johannes Huber
(Specialist in gynecology and obstetrics, Vienna, Austria)
«The study confirms the statement of the European Food Safety Authority (EFSA) which studied the ingredients of red clover extracts for their side effects with regard to breast, thyroid and endometrium. It determined that none of the three organ systems are afflicted, damaged by or at risk from these plant substances. The results furthermore show that isoflavones clearly also have an aromatase inhibiting effect, which should be further evaluated in future.»
Imhof M. et al., Maturitas 2006 55: 76-81.
Senior Physician Dr. Markus Lipovac
(Department for gynecology, General Public Teaching Hospital
Korneuburg)
«In contrast to soy, in addition to the active components of genistein and daidzein, red clover also contains their precursors biochanin A and formonenetin. In this study, for the first-time detailed data was collected on the metabolization of a red clover extract (MF11RCE®) and the bioavailability of its metabolites in oral administration. The results confirm that a single daily dose of 80mg red clover extract is suitable for the long-term and reliable treatment of menopausal symptoms.»
Lipovac M. et al., Fitoterapia 2015 Sep 105: 93-101.
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